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Other🔬 55% confidence · 400 studies

AKG (Calcium Alpha-Ketoglutarate)

Krebs cycle metabolite that declines with age. Supports energy metabolism and may reduce chronic inflammation.

🌅 Morning🍽️ Empty stomach👤 +18 years

What is it for?

🧬
Slow aging

Healthspan extension in mice. Mechanism via epigenetics

Low evidence

💡 Absorption: The Ca-AKG form is the one studied for longevity. Take on empty stomach. 300-1000mg/day.

⚠️ Caution: Generally safe. Natural body metabolite.

Recommended doses

Anti-aging1000 mg

Range: 300 – 1000 mg

Ca-AKG (Calcium Alpha-Ketoglutarate). On an empty stomach

📚 Scientific references (3)▼
Alpha-Ketoglutarate Supplementation and Biological Age in Middle-Aged Adults (ABLE): Randomized Controlled Trial Protocol(2023)

Protocolo de ensayo clínico aleatorizado doble ciego con Ca-AKG 1g/día vs. placebo durante 6 meses en 120 adultos de 40-60 años, midiendo reducción de la edad biológica por metilación del ADN.

Rejuvant Ca-AKG Conferred an Average 8-Year Reduction in Biological Aging After 7 Months of Use(2022)

Estudio observacional de 42 individuos tomando alfa-cetoglutarato de calcio con vitaminas que mostró reducción promedio de 8 años en la edad biológica según el test de metilación TruAge.

Alpha-ketoglutarate extends healthy lifespan in C57BL/6 mice(2020)

Estudio Buck Institute. Ca-AKG extendio vida saludable en ratones un 12%, redujo fragilidad y mejoro salud metabolica.

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Product comparator (3)

Sorted by cost per dose, from cheapest to most expensive

💰 Best price per dose
Source of Nature Ca-AKG 500mg - 60 Capsulas
Source of Nature Ca-AKG 500mg - 60 Capsules

Source of Nature GB

12.49€0.21€/dose~6.25€/month
💊 500mg Ca-AKG📦 60 servings★ 4.5
Amazon🚚 Free with Prime
Buy
CaAKG 1100mg Alta Dosis - 120 Capsulas Veganas
CaAKG 1100mg High Dose - 120 Capsules Vegan

Vit4ever DE

28.49€0.24€/dose~7.12€/month
💊 1100mg Ca-AKG📦 120 servings★ 4.6
Amazon🚚 Free with Prime
Buy
Youth & Earth Calcium AKG 500mg - 60 Capsulas
Youth & Earth Calcium AKG 500mg - 60 Capsules

Youth & Earth GB

23.61€0.39€/dose~11.80€/month
💊 500mg Ca-AKG📦 60 servings★ 4.7
Amazon🚚 Free with Prime
Buy

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