Other🔬 70% confidence · 2000 studies

NAD+ Precursors (General)

Group of compounds that raise NAD+ (nicotinamide adenine dinucleotide) levels, an essential coenzyme that declines ~50% between ages 40 and 60. Includes NMN, NR, and niacin.

🌅 Morning🍽️ Any👤 +18 years

💡 Absorption: NMN and NR are the direct precursors. Niacin (B3) also raises NAD+ but with less specificity. Combining with resveratrol potentiates the effect via sirtuins.

⚠️ Caution: See individual precautions for NMN and NR. The concept of raising NAD+ is well supported but optimal methods are still debated.

📚 Scientific references (3)▼

Nicotinamide riboside elevates NAD+ in humans (Martens CR et al., Nat Commun)(2018)

NR supplementation raises NAD+ levels and may improve cardiovascular function.

NAD+ repletion improves mitochondrial function (Rajman L et al., Cell Metab)(2018)

Review of NAD+ precursors (NMN, NR) for mitochondrial health and aging.

NAD+ metabolism and its roles in cellular processes (Verdin E, Science)(2015)

Comprehensive review of NAD+ biology and its decline with aging.

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