Omega-3 (EPA/DHA)
Omega-3 fatty acids EPA and DHA are essential for cardiovascular and brain health and reducing inflammation. They are obtained primarily from fish oil or algae.
What is it for?
Reduces triglycerides and protects the heart
DHA minimum 200-300mg for fetal brain development
Reduces chronic inflammation, a key driver of aging. Protects telomere length.
DHA passes into breast milk. Important for infant brain development
Multi-systemic benefits
Potent anti-inflammatory. Reduces pelvic pain and prostaglandins
DHA is a structural component of the brain
Reduces inflammation and elevated triglycerides common in PCOS
Reduces post-exercise inflammation
Reduces joint inflammation
Anti-inflammatory that can reduce menstrual pain
Can improve protein synthesis
Can improve fat oxidation
Maintains lipid barrier
Anti-inflammatory effect may reduce risk. Mixed but promising evidence in colorectal cancer.
Stress-modulating effect
Post-menopausal cardiovascular protection
Improves mood, inflammation and cardiovascular health
DHA essential for fetal brain development
Anti-inflammatory that can modulate allergic response
💡 Absorption: Take with the main meal to reduce fishy burps and improve absorption. Triglyceride forms are better absorbed than ethyl ester forms.
⚠️ Caution: May increase bleeding time. Consult a doctor if taking anticoagulants. Choose brands with purity certification. In those under 18, use only under medical/pediatric supervision.
Recommended doses
Range: 500 – 3000 mg EPA+DHA
Minimum 500mg combined
Range: 2000 – 4000 mg EPA+DHA
Higher proportion of EPA
Interactions with other supplements
Both have anticoagulant effects. Combined, they may increase the risk of bleeding.
⚕️ Medication interactions
Omega-3 at high doses (>3g/day) can enhance the anticoagulant effect and increase the risk of bleeding.
→ Consultar médico. Monitorizar INR. No superar 2g/día sin supervisión.
Combination may increase the risk of bleeding due to additive antiplatelet effect.
→ Consultar médico si toma aspirina diaria.
Omega-3 has an antiplatelet effect that may add to that of clopidogrel, increasing the risk of bleeding.
→ Consultar cardiólogo. Evitar dosis altas de omega-3 (>2g/día). Vigilar signos de sangrado.
🏥 Contraindications
Omega-3 a dosis altas tiene efecto antiagregante plaquetario que puede empeorar trastornos de la coagulación.
→ Consultar hematólogo antes de suplementar. Si se autoriza, no superar 1g/día y vigilar signos de sangrado.
📚 Scientific references (4)▼
Meta-analisis de 149,051 participantes. Omega-3 asociado a reduccion de mortalidad cardiovascular, infarto no fatal y eventos coronarios.
Revision Cochrane de RCTs. Pequeno beneficio de omega-3 (especialmente EPA) en depresion comparado con placebo.
Revision sistematica actualizada. EPA puro puede ser mas efectivo que combinaciones EPA+DHA. Dosis altas (>2g) reducen trigliceridos significativamente.
Revision Cochrane. Evidencia moderada de reduccion de trigliceridos y eventos coronarios. Poca evidencia para mortalidad total.
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