Riboflavin (B2)
Vitamin B2 essential for energy metabolism and as a cofactor for glutathione reductase. At high doses (400mg) it is effective for migraine prevention.
💡 Absorption: Absorption limited to ~27mg per dose. High doses for migraines (400mg) are split. Urine turns bright yellow (normal).
⚠️ Caution: No established UL. Yellow urine is harmless. No known toxicity even at high doses.
📚 Scientific references (3)▼
Riboflavin status modulates the effect of MTHFR genotype on homocysteine levels.
Higher riboflavin intake is associated with reduced risk of age-related cataracts.
Riboflavin 400mg/d reduces migraine frequency by 50% in 59% of patients.
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