Ashwagandha KSM-66 Ecologica 600mg - 180 Capsules

Pharmacopeias are essential for ensuring the quality of botanical raw materials, yet their utility is limited by slow adaptation to rapid innovation in the dietary supplement industry. Challenges arise from differing standards (e.g., the British Pharmacopoeia (BP) and the United States Pharmacopoeia (USP)), as well as a critical lack of comparative data for globally sourced ingredients. The post-COVID surge in adaptogens, such as ashwagandha, underscores the urgency of these issues. The commercial use of aerial parts-despite traditional root-only use and phytochemical variability-raises concerns about quality and safety. The situation necessitates rigorous source verification and re-evaluation of current pharmacopeial methods. To address these deficiencies, we developed and compared an HPLC-PDA method utilizing BP and USP standards to quantify three steroidal lactones (withaferin A, withanolide A, and withanoside IV) in ashwagandha samples and commercial products. Our analysis revealed substantial variations in steroidal lactone content. Alarmingly, over 44% of products failed to meet BP standards, and 60% failed to meet USP standards. The high failure rate was attributed to the elevated presence of co-eluted dihydrowithaferin sulfate, primarily found in leaf samples, which led to an underestimation of withanolide A. Only 10 of 25 supplement products met both standards; only two were confirmed as root-derived, while the remainder contained varying proportions of (un)disclosed aerial parts. These findings highlight critical plant-part-specific chemical variations and the need for enhanced source verification and improved quality control. Developing robust analytical methods and revisiting existing pharmacopeial guidelines are crucial for assessing the quality and safety of ashwagandha products, including novel formulations.

Background: The poultry production systems have led to marked increase in the production of poultry meat and eggs worldwide. The use of various phytobiotic feed additives as dietary supplements may have positive effect on poultry performance, carcass quality and economic benefit in poultry birds. Methods: A feeding trial of 42 days was conducted at Veterinary College, Navania, Udaipur in the year 2021 using 300, day-old broiler chicks (Cobb-400) randomly distributed in completely randomized design. The broiler chicks were divided randomly into ten treatment groups with three replicates under each treatment. The T1 i.e. control group was fed on basal diet, while T2 was supplemented with Oxytetracycline (OTC) powder @ 0.1g/kg feed. T3 and T4 were served as Basal diet supplemented with Garlic powder @ 0.75% and @ 1.50%. T5 and T6 were served as Basal diet supplemented with Ashwagandha root powder @ 0.75% and @ 1.50%. T7 and T8 were served as Basal diet supplemented with Shatavari root powder @ 0.75% and @ 1.50%. T9 was served as Basal diet supplemented with Garlic powder @ 0.25%, Ashwagandha root powder @ 0.25% and Shatavari root powder @ 0.25%. T10 was served as Basal diet supplemented with Garlic powder @ 0.50%, Ashwagandha root powder @ 0.50% and Shatavari root powder @ 0.50%. Result: The supplementation of Garlic powder, Ashwagandha root powder and Shatavari root powder alone and in combination had highly significant (P less than 0.01) effect on body weight, dressing percentage, weight of liver, heart, Gizzard and Giblet but significant (P less than 0.05) effect was observed on eviscerated yield. The net return per bird profit was found higher in T9 group.

College of Kinesiology Research Theme: Human Performance. Ashwagandha, an herbal supplement commonly used for stress reduction and general well-being, has gained attention in sports science for its potential role in muscle recovery. This study examined the short-term effects of ashwagandha supplementation on muscle recovery by assessing muscle strength, soreness, and swelling over a 72-hour period following resistance exercise. Ten healthy adults (ages 18–35 years) participated in a randomized, double-blind, placebo-controlled study. Participants were assigned to either a 600 mg/day ashwagandha supplementation group or a placebo group, receiving a vitamin B pill, for seven days before completing an acute resistance exercise protocol targeting the biceps. Muscle recovery was assessed using ultrasound (muscle thickness), a Biodex machine (torque), and subjective soreness ratings (Visual Analog Scale). Follow-up assessments occurred at 24-, 48-, and 72-hours post-exercise. Results of a 2 (group) × 5 (time) repeated-measures ANOVA revealed a significant group × time interaction for muscle thickness (p = 0.013). Post-hoc analysis indicated that muscle thickness in the ashwagandha group returned to baseline within 24 hours, whereas the placebo group exhibited persistent swelling at 24-, 48-, and 72-hours post-exercise (p < 0.05). No significant interaction was found for torque recovery, though a time main effect (p < 0.01) indicated that strength declined post-exercise and recovered by 48 hours in both groups. Similarly, muscle soreness followed a typical time-dependent recovery pattern, peaking at 24 hours and declining at 48 and 72 hours (p < 0.05), with no significant difference between groups. These findings suggest that short-term ashwagandha supplementation may accelerate muscle swelling reduction but does not significantly impact strength recovery or muscle soreness compared to placebo. Due to the small sample size, further research is necessary to confirm these r

An attempt has been made to ascertain the impact of the homeopathic medication Withania somnifera on the level of tissue protein and weight gain in Channa gachua. A 30-day feeding trial was conducted to investigate the impact of Withania somnifera, an herbal supplement, on the diet. The quantity of protein in the muscles, liver, and ovaries of the fish under treatment and the control group was measured. The amount of protein in the fish’s liver and muscle that received ashwagandha treatment did not significantly increase. On the other hand, the ovary displayed a noticeably higher protein content per gram of tissue. The amount of tissue protein in the ovary after it is fed an experimental diet causes the ovary to mature prematurely.